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New York • Champion at Wimbledon in both singles and doubles. Winner again at the All England Club in both events, four weeks later at the London Olympics.

Nobody would blame Serena Williams if she felt worn down by this year's jam-packed tennis calendar. She doesn't see it that way, though — even with the grind of the U.S. Open looming.

"I look forward to this," Williams said. "It's almost as like a launching pad for what I want to do for the rest of the hard-court season."

In a way, yes, Monday's start of the year's last Grand Slam actually marks something of a new beginning — the kickoff of a six-month stretch on the hard courts that winds down at the 2013 Australian Open.

Call it mental gymnastics, a creative way of looking at things or whatever else might apply. What can't be denied is that in an Olympic year, the U.S. Open — considered the toughest test in tennis even under normal circumstances — is essentially the season's fifth major.

"A lot of them," Jim Courier said, "are running on fumes."

Indeed, many top players have had to double down on their fitness and find new, creative ways of organizing their schedules to get ready for what they hope will be a two-week grind in the fishbowl that is Flushing Meadows.

Defending champion Novak Djokovic barely took any time off following his fourth-place finish at the Olympics. He traveled to Toronto for a hard-court tuneup, played six matches and won the tournament. Then, he flew to Cincinnati, played six more matches but lost to Roger Federer in the final. No shame there, though that loss to Federer did include an uncharacteristic 6-0 whitewashing in the first set.

"Mentally, I wasn't there, wasn't fresh," Djokovic said. "It had been a very busy time starting at the Olympic Games, and maybe that caught up with me at the end."

No big deal in Cincinnati. But a half-hour mental lapse in New York could mean the end of Djokovic's quest to win what has, essentially, shaped up as the tiebreaker major for 2012.

Second-seeded Djokovic won the Australian Open. Rafael Nadal won the French Open. Top-seeded Federer won Wimbledon. Just for good measure, third-seeded Andy Murray won the Olympics, meaning the U.S. Open could essentially determine the player of the year in men's tennis.

Some combination of Nadal, absent this year because of a knee injury, and the other three — Djokovic, Federer and Andy Murray — have occupied every spot in the finals of the past eight Grand Slam tournaments.

Who has the most to gain over this fort night? John McEnroe thinks it's Murray, who has the Olympic gold, but is still in search of his first Grand Slam title.

"The way it pans out, it's conceivable that Murray could make an argument were he to win this ... that you could say he's the best player in the world this year," McEnroe said. "To me, that's an unbelievabl upside."Murray opens Monday in Arthur Ashe Stadium against Alex Bogomolov Jr. of Russia.

Federer, back at the top of the rankings after 25½ months during which Nadal and Djokovic took the spot from him, has a night match Monday against American Donald Young, who is 3-21 this season.

-The Associated Press