Del Negro had a 128-102 regular-season record in three years with the team. The Clippers made the playoffs the last two seasons, including last year when they advanced to the second round for only the second time since the franchise moved to Los Angeles in 1984.
This season, the Clippers won a franchise-record 56 games, had a 17-game winning streak and won the club's first Pacific Division title before their early playoff exit. They led Memphis 2-0 before losing in six games.
All-Star guard Chris Paul becomes a free agent July 1, and the Clippers have said their top priority is to re-sign him.