The defense even helped BenJarvus Green-Ellis get into the end zone for the game's only touchdown in a 13-6 victory over the previously undefeated Patriots.
It was so impressive that defensive coordinator Mike Zimmer was handed a rain-drenched game ball in the locker room.
"That's a great accomplishment," coach Marvin Lewis said. "I don't normally give out game balls, but I gave that one to Zimmer. They played well today. They were tight in coverage most of the day. Upfront, they got after it."
Geno Atkins sacked Brady on his first pass attempt, and the Bengals (3-2) dropped him four times overall. And that wasn't all: New England (4-1) failed to get into the end zone after a first-and-goal from the 1-yard line in the fourth quarter.
One yard too much for New England? Stunning.
"I'm bummed that we lost," Brady said of his broken streak. "I think that's all that really matters."
A driving rain moved in just before New England's final chance. After a couple of dropped passes, Brady threw one toward the goal line and Adam "Pacman" Jones made a juggling interception inside the Cincinnati 5-yard line.
"We knew we were going to have our hands full, but we were able to get to Brady on the second play," defensive tackle Domata Peko said. "After that, you could see he was a little shaky. If you hit somebody enough, they're going to make mistakes."
Brady had thrown a touchdown pass in 52 straight games, the second-longest streak in NFL history behind Drew Brees' 54-game streak.