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Melbourne, Australia • After letting the distraction of Rafael Nadal's painful back problems cost him a set, Stan Wawrinka regained his composure to win his first Grand Slam title with a 6-3, 6-2, 3-6, 6-3 victory Sunday in the Australian Open final.

The 28-year-old Swiss player had never taken a set off Nadal in 12 previous meetings, but attacked from the start against the 13-time major winner.

"It's really not the way you want to win a tennis match, but in a Grand Slam final I'll take it," Wawrinka said.

Nadal appeared to be on the verge of retiring in the second set, when he hurt his back and needed a medical timeout, but he refused to quit.

The left-handed Spaniard was a hot favorite to win the title and become the first man to win each of the four Grand Slam tournaments twice in the Open era — instead, his injury curse struck again in Australia. It remains the only major he's hasn't won at least two times.

"Rafa, I'm really sorry for you, I hope your back is going to be fine, you're a really great guy, good friend and really amazing champion," Wawrinka said as he accepted his first major trophy. "Last year I had a crazy match, I lost it. I was crying a lot after the match. But in one year a lot happened — I still don't know if I'm dreaming or not but we'll see tomorrow morning."

Wawrinka lost in five sets to Novak Djokovic in the fourth round of the 2013 Australian Open, in the longest Grand Slam match of the season. Djokovic went on to win his third consecutive title at Melbourne Park, and then beat Wawrinka again in five sets in the U.S. Open semifinals.

But Wawrinka avenged those losses this time, beating Djokovic in the quarterfinals and then beating seventh-seeded Tomas Berdych in the semis. Now, after being the first man in 21 years to beat the No. 1 and No. 2-ranked players en route to a major title, Wawrinka will move from No. 8 to No. 3.

In doing so, he'll surpass 17-time Grand Slam winner Roger Federer — who lost to Nadal in the semifinals — to become the highest-ranked Swiss player for the first time in his career.

"I need to say many thanks to Stan, you really deserve it," Nadal said. "Luck was against me today but you really deserve it.

"Last thing that I wanted to do was retire. I hate to do that, especially in a final. Same time, [it is] tough to see yourself during the whole year you are working for a moment like this, and arrives the moment and you feel that you are not able to play at your best."

Nadal has had a terrible stretch with injuries at the Australian Open. He won the title in 2009, and lost an epic five-set final to Djokovic in 2012. But he missed the 2013 edition with knee injuries and illness, and his quarterfinal losses in 2010 and 2011 were affected by injuries. —

Storylines Swiss bliss in Australia

R Stan Wawrinka defeats Rafael Nadal 6-3, 6-2, 3-6, 6-3 for the Australian Open title.

• Nadal suffers a back injury in the second set and struggles to finish.