Baltimore's Justin Tucker missed a 67-yard field goal on the game's final play after missing a 66-yarder earlier in the game.
The touchdown and conversion gave Rice a comeback after Philadelphia quarterback Nick Foles threw a 12-yard touchdown to Cleveland tight end Jordan Cameron with less than 5 minutes to play to give Sanders a 21-14 lead.
The touchdowns by Cameron and Murray were the only scores of the second half in a game that had eight turnovers including six interceptions and nine sacks.
"It was definitely sloppy. There was a lot of turnovers because of the weather," said Houston defensive end J.J. Watt, who was a captain on Sanders' team. "There was a lot of rain, so obviously that factored into it."
Foles was the only quarterback of six in the game to not throw an interception. He was named offensive MVP, finishing with seven completions for 89 yards.
Philadelphia receiver DeSean Jackson and Carolina quarterback Cam Newton also scored touchdowns for Team Sanders. New Orleans tight end Jimmy Graham and Cleveland receiver Josh Gordon caught touchdowns for Team Rice.
The Pro Bowlers were split up by the NFL greats in a new draft format meant to improve the game. The picks made earlier in the week created matchups that pitted usual teammates against each other and challenged Rice and Sanders to compare the all-stars against one another. That led to plenty of trash talk between Rice and Sanders and some bruised egos among players used to being on top of their sport.
The result was a game that appeared more competitive than in years past, with some big hits even between teammates and fewer shenanigans. "It was crazy, but we had fun with it," Gordon said.