Mike Napoli homered and Felix Doubront (1-2) went 6 2-3 innings for the Red Sox, who scratched star second baseman Dustin Pedroia before the game due to a sore left wrist.
New York, playing without Derek Jeter for the second consecutive game, scored its third run with the benefit of instant replay in the fourth.
With runners at the corners and one out, the Red Sox thought they turned an inning-ending double play on Francisco Cervelli's grounder. First base umpire Bob Davidson called Cervelli out on a bang-bang play, and Cervelli grabbed his right hamstring as he tumbled to the ground.
Yankees manager Joe Girardi challenged the call, which was overturned after a 3-minute replay review. That gave New York another run and a 3-1 lead.
Farrell, surely still bothered by a replay review that curiously went against Boston the day before, pointed to his eyes as he argued with two umpires. He was quickly ejected by Davidson.
ATHLETICS 3, MARINERS 0
SEATTLE • Yoenis Cespedes hit a two-run homer that broke a scoreless tie in the eighth inning, lifting Oakland over Seattle.
Cespedes pulled a 2-2 slider from Charlie Furbush (0-1) into the left field bullpen. Cespedes' second homer of the season came after Jed Lowrie drew a leadoff walk.
Josh Donaldson added a solo home run in the ninth, his third, off Lucas Luetge.
A's starter Scott Kazmir pitched two-hit ball for six innings, striking out nine without a walk.
Dan Otero (2-0) retired two batters in the seventh. Luke Gregerson worked the eighth and Sean Doolittle allowed one hit in the ninth for his first save.
Chris Young made his first start since Sept. 9, 2012, while with the New York Mets. Young pitched six shutout innings, giving up four hits. He walked three and struck out two.
RANGERS 1, ASTROS 0
ARLINGTON, Texas • Martin Perez threw eight scoreless innings, Donnie Murphy had a sacrifice fly and the Rangers got a series-clinching victory over the Astros.
Perez (2-0) scattered five hits and walked three, but the left-hander benefited from four double-play grounders. He struck out two.
Murphy's deep flyball to the left-center gap in the sixth sent home Josh Wilson for the lone run of the game against Brett Oberholtzer (0-3).
Alexi Ogando worked a perfect ninth to convert his first save chance.
BLUE JAYS 11, ORIOLES 3
BALTIMORE • Mark Buehrle allowed one run over seven innings to win his third straight start, and the Blue Jays hit three home runs and had a season-high 17 hits in an victory over the Orioles.
Jose Bautista hit a three-run drive and Colby Rasmus and Brett Lawrie had solo shots to help Toronto win the decisive matchup of the three-game series.
Rasmus, Edwin Encarnacion and Adam Lind each collected three hits for the Blue Jays, who enjoyed their highest scoring game of the year at the expense of Ubaldo Jimenez (0-3) and three Baltimore relievers.
Buehrle (3-0) gave up five hits, walked none and struck out two.
Chris Davis hit his first homer of the season for Baltimore.
TWINS 4, ROYALS 3
MINNEAPOLIS • Pitcher Wade Davis made a wild flip home on a comebacker in the eighth inning and the Twins rallied past the City Royals for a three-game sweep.
A madcap sequence put the Twins ahead and a crazy play ended it, too.
With two outs and none on in the ninth, Mike Moustakas popped a ball straight up. As he stood to watch it in the batter's box, catcher Kurt Suzuki tripped over him, resulting in an interference call for the final out.
After the Royals scored three times in the eighth for a 3-2 lead, reliever Aaron Crow (0-1) walked two Minnesota batters to start the bottom half.
Davis struck out Joe Mauer, but Trevor Plouffe walked to load the bases. Chris Herrmann then hit a tapper back to the mound and Davis' toss sailed past catcher Salvador Perez. Pedro Florimon scored the tying run and Brian Dozier slid home under Perez's return throw to Davis covering the plate.
Casey Fien (1-0) got one out and Glen Perkins posted his third save.
WHITE SOX 4, INDIANS 3
CHICAGO • Alexei Ramirez hit a two-run homer off John Axford in the ninth inning, rallying the White Sox over the Indians.
The Indians scored twice in the top of the ninth, getting the go-ahead run on a wild pitch by closer Matt Lindstrom (1-1).
Axford (0-1) came in seeking his fifth save in as many chances. He issued a leadoff walk to Jordan Danks, who stole second.
One out later, Ramirez homered over the left field fence.
ANGELS 14, METS 2
ANAHEIM, Calif. • Mike Trout, Albert Pujols and Raul Ibanez hit consecutive home runs off Bartolo Colon in the first inning, setting the tone for the Angels' rout of the Mets in the decisive game of their interleague series.
Hank Conger also went deep against Colon, who won the AL CY Young Award in 2005 with the Angels. Colon (1-2) gave up nine runs and 11 hits in five innings, allowing at least one hit to every batter in the Angels' starting lineup.