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St. Louis Rams quarterback Sam Bradford has a torn ACL in his left knee for the second straight year and is out for the season.
Coach Jeff Fisher confirmed the extent of the injury Sunday night, news first reported by ESPN and the St. Louis Post-Dispatch.
"We lost our quarterback," Fisher said. "For Sam, it was devastating."
In all, five starters were hurt against the Browns.
Cornerback Trumaine Johnson was carted off with a knee injury and three others guard Rodger Saffold and defensive tackles Kendall Langford and Michael Brockers left with ankle injuries.
Johnson will be out 4-6 weeks with an MCL tear, but Fisher said Saffold, Langford and Brockers could play if needed in the preseason finale Thursday at Miami.
Bradford was injured in the first quarter of Saturday night's 33-14 preseason victory at Cleveland. He was hit on his left side by Browns defensive end Armonty Bryant as he threw a pass.
Bradford hopped briefly on his right leg before dropping to the ground.
Bradford, the first overall pick of the 2010 draft, missed the last nine games last season after getting injured at Carolina. Veteran Shaun Hill is the backup and the Rams also have rookie Garrett Gilbert and Austin Davis on the roster.
"Shaun's our guy," Fisher said. "I brought him here."
Washington cuts BYU's Hoffman
Former BYU receiver Cody Hoffman was among nine players cut by Washington on Sunday. The 6-foot-4 Hoffman who was signed as an undrafted free agent in May had 260 receptions for 3,612 yards and 33 touchdowns at BYU, all school records for a career. Washington also cut veteran linebacker Rob Jackson.
Around the league
Bears • Chicago cut Jordan Palmer, making Jimmy Clausen the backup quarterback behind Jay Cutler. Clausen signed with Chicago in June and won the backup job with a solid camp. He appeared in 13 games for Carolina from 2010 to 2013 after starring at Notre Dame.
Bills • Buffalo released veteran defensive lineman Alan Branch on Sunday, one day after he was arrested on a drunken-driving charge.
Dolphins • Hall of Fame quarterback Dan Marino is returning to Miami as a special adviser to Dolphins owner Stephen Ross.
Broncos • Denver parted ways with 11 players, including nine-year veteran tackle Winston Justice and undrafted rookie running back Brennan Clay of Oklahoma. The moves reduced Denver's roster to 77 players with two more cuts due by Tuesday.