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Philadelphia • Achraf Yacoubou hit the tiebreaking 3-pointer late in the second half to help Villanova upset No. 5 Louisville 73-64 on Tuesday night.
The Wildcats (12-7, 3-3 Big East) led by as many as 10 points in the first half and rallied late in the second to send the Cardinals to their second straight loss. Louisville (16-3, 4-2) had an 11-game winning streak end in a 70-68 loss to Syracuse on Saturday.
Ryan Arcidiacono scored 15 points, and JayVaughn Pinkston and Mouphtaou Yarou each scored 11 for Villanova.
The Wildcats students packed behind each basket stormed the court in a wild celebration for a win coach Jay Wright's struggling program badly needed.
Yacoubou hit the go-ahead 3 with just less than 4 minutes left, and the Wildcats held on from there.
"We know how good they are," Wright said of Louisville. "We still think that team can win a national championship."
Peyton Siva had 15 points and 13 assists for the Cardinals and Wayne Blackshear scored 17 points. The Cardinals didn't play like a team that was just the No. 1 team in the country. The Cardinals, a 71 percent free-throw shooting team, were 12 of 24 from the line and shot 40 percent from the field.
Wright's program has fallen from among the Big East's elite following a run to the 2009 Final Four.
No. 3 Kansas 59, No. 11 Kansas State 55 • In Manhattan, Kan., Travis Releford scored 12 points and Kansas held off Kansas State down the stretch for a victory that gave the Jayhawks sole possession of first place in the Big 12. Ben McLemore and Jeff Withey added 11 points each for the Jayhawks (17-1, 5-0 Big 12), who pushed their nation-leading winning streak to 16 games and ended the Wildcats' 12-game home winning streak.
Shane Southwell scored a career-high 19 points for Kansas State (15-3, 4-1).
No. 13 Michigan State 49, Wisconsin 47 • In Madison, Wis., Keith Appling scored 19 points and Branden Dawson added 18 for Michigan State.
• No. 3 Kansas 59, No. 11 Kansas State 55
• Villanova 73,No. 5 Louisville 64
• No. 13 Michigan State 49, Wisconsin 47
• Wake Forest 86, No. 18 N.C. State 84
• No. 22 Missouri 71, South Carolina 65