Isaac Redman added a late 2-yard touchdown run for Pittsburgh, which had little trouble avoiding its first 0-2 start in a decade.
The Jets (1-1) did little offensively after a pair of early scoring drives. Mark Sanchez passed for 138 yards and a touchdown, but New York hardly looked like the offensive juggernaut that piled up points in a 48-28 opening-week blowout win over Buffalo.
Tim Tebow appeared on just one drive early in the second half for the Jets, running for 22 yards on his first carry. It wasn't nearly enough against a defense that did just fine without injured stars James Harrison and Troy Polamalu.
Keeping the New York offense off the field for long stretches certainly helped. So did a handful of dropped passes by Jets receivers and missed tackles.
With Roethlisberger expertly running new offensive coordinator Todd Haley's versatile system, he picked apart a Jets secondary that looked exposed without injured star cornerback Darrelle Revis. Roethlisberger completed passes to 10 different receivers as Pittsburgh converted 8 of 15 third downs and held the ball for more than 36 minutes.
The Steelers led 13-10 early in the third quarter when Roethlisberger needed just five plays to lead them 59 yards. Facing third-and-16 at New York's 37, Roethlisberger stepped up in the pocket and heaved it to Wallace. The Pro Bowl wide receiver let Jets cornerback Antonio Cromartie fly by, then snatched the ball out of the air while keeping both feet in bounds.
Trailing by 10, the Jets went to Tebow, who engineered a 29-23 upset win by the Denver Broncos over the Steelers in the playoffs last January. He needed just two plays to put the Jets in Pittsburgh territory, but the drive soon stalled.
After a 6-yard loss by Shonn Greene, Sanchez ran back into the huddle. Two incompletions later, the Jets were punting and didn't take another meaningful snap in Pittsburgh territory the rest of the game.
Sanchez completed just 10 of 27 passes and was a miserable 6 of 17 in the second half, with two of those completions coming on a last-second stat-padding drive.
By then, the Steelers had regained the sense of urgency they lacked in an opening week loss to the Broncos. Taking over at their own 25 with 13:47 remaining, Pittsburgh took more than 10 minutes off the clock on a 75-yard touchdown drive, with Redman capping it by surging off right tackle for the score.
The one-sided ending was far different than a mostly even first half.
A meeting of two of the league's better defenses lacked considerable star power due to injuries. Pittsburgh sat Harrison (right knee) and Polamalu (strained right calf) while Revis didn't make the trip due to a concussion sustained last week.
With the three perennial Pro Bowlers sidelined, the offenses took advantage, trading a series of sustained scoring drives during a back-and-forth first half.
The Jets took leads of 7-3 and 10-6 behind steady play from Sanchez. He hit Santonio Holmes for a 14-yard touchdown pass to cap a 90-yard drive then put together a 12-play, 61-yard march that was capped by Nick Folk's 38-yard field goal.
The Steelers climbed back in front late in the half, with Roethlisberger leading them 80 yards in 11 plays, the last one a simple lob to Miller that put the Steelers up 13-10.
New York took over at its 31 after the ensuing kickoff with 57 seconds left before the break. Even though the Jets had two timeouts remaining and decent field position, they chose to sit on the ball. It would be a scene they would repeat only unintentionally in the second half.
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N.Y. Jets 10, Pittsburgh 27
N.Y. Jets 7 3 0 0 10
Pittsburgh 3 10 7 7 27
Pit • FG Suisham 45, 9:07.
NYJ • Holmes 14 pass from Sanchez (Folk kick), 4:19.
Pit • FG Suisham 45, 14:56.
NYJ • FG Folk 38, 9:35.
Pit • Miller 1 pass from Roethlisberger (Suisham kick), 1:03.
Pit • Wallace 37 pass from Roethlisberger (Suisham kick), 8:44.
Pit • Redman 2 run (Suisham kick), 3:34.
Attendance • 64,511.
First downs 16 21
Total Net Yards 219 331
Rushes-yards 22-90 28-66
Passing 129 265
Punt Returns 3-6 2-23
Kickoff Returns 4-112 2-45
Interceptions Ret. 0-0 0-0
Comp-Att-Int 10-27-0 24-31-0
Sacked-Yards Lost 2-9 3-10
Punts 6-45.3 5-41.0
Fumbles-Lost 1-1 0-0
Penalties-yards 7-63 10-107
Time of Possession 23:24 36:36
Rushing • N.Y. Jets, Powell 9-33, Greene 11-23, Tebow 1-22, McKnight 1-12. Pittsburgh, Dwyer 12-28, Redman 12-25, A.Brown 1-9, Rainey 2-3, B.Batch 1-1.
Passing • N.Y. Jets, Sanchez 10-27-0-138. Pittsburgh, Roethlisberger 24-31-0-275.
Receiving • N.Y. Jets, Holmes 3-28, Kerley 2-67, Reuland 2-20, Cumberland 2-13, Gates 1-10. Pittsburgh, A.Brown 7-79, Wallace 5-74, Sanders 3-33, Miller 3-19, W.Johnson 1-26, Redman 1-14, Dwyer 1-12, Pope 1-7, Cotchery 1-6, Rainey 1-5.
Missed Field Goals • None.