The Spartans (21-4, 10-2 Big Ten) broke a first-place tie in the conference with No. 1 Indiana, which plays at Michigan State next Tuesday after the Spartans try to avoid a letdown Saturday night at Nebraska.
Michigan State's Keith Appling acknowledged he was a little bit surprised by the lopsided victory the school's largest since beating Michigan by 27 points in 2002 but shrugged off the significance of it with much of the regular season remaining.
"We just have to take it for what it is and prepare for our next game," Appling said.
The Wolverines (21-4, 8-4) have lost three of four, but the closely contested setbacks on the road against the Hoosiers and at Wisconsin were nothing like the latest when they were held to a season-low point total.
"It was an embarrassing loss," guard Trey Burke said.
No. 7 Florida 69, No. 25 Kentucky 52 • Scottie Wilbekin had 14 points and eight assists, and Pat Young recorded his sixth double-double of the season in Gainesville, Fla.
The Gators (20-3, 10-1 Southeastern Conference) snapped a five-game losing streak in the series, and coach Billy Donovan improved to 2-7 against Kentucky's John Calipari.
• No. 8 Michigan St. 75, No. 4 Michigan 52
• No. 7 Florida 69, No. 25 Kentucky 52