Normandy Invasion faded to fourth.
Orb, the 5-1 favorite, ran the 1¼ miles in 2:02.89
Orb paid $12.80, $7.40 and $5.40. Golden Soul returned $38.60 and $19.40 while Revolutionary paid $5.40 to show.
Todd Pletcher had a record-tying five runners. Revolutionary was the best of the "Todd Squad," followed by Charming Kitten (ninth), Overanalyze (11th), Palace Malice (12th) and Verrazano (14th).
Goldencents, owned in part by Rick Pitino, coach of Louisville's national basketball champions, finished a 17th. His jockey, Kevin Krigger, was trying to become the first black rider to win the race since 1902.
Rosie Napravnik was also bidding to make history as the first woman jockey to win the world's biggest horse race. She finished fifth aboard Mylute, the highest finish by a female rider.
D. Wayne Lukas, who won the Derby four times and would have been the oldest trainer to saddle a winner, sent out two runners. Oxbow, with three-time Derby winning jockey Gary Stevens aboard, finished sixth. Will Take Charge was eighth.
Lines of Battle from Ireland finished seventh, denying European champion trainer Aidan O'Brien the international victory.