Los Angeles finished strong in a stretch of four games in five days, posting the biggest margin of victory over Chicago in franchise history.
Luol Deng scored 22 points as the Bulls got off to a rough start to their latest stretch without Rose, who tore cartilage in his right knee Friday night in Portland.
The 2011 NBA MVP headed home to Chicago to prepare for surgery on Monday, when Chicago should find out how long he'll be sidelined.
Kirk Hinrich had nine points and seven assists while starting in place of Rose, who missed last season while recovering from surgery on his left knee.
LAKERS 100, KINGS 86
LOS ANGELES • Reserve forward Xavier Henry scored 12 of his 21 points in the fourth quarter and Pau Gasol had 20 points and 10 rebounds to lead Los Angeles over Sacramento.
Steve Blake finished with 12 assists, nine points and five rebounds. Blake, who has started all 14 games for the Lakers at point guard in place of the injured Steve Nash, has recorded double digits in assists in each of the last five.
The Lakers, back at .500 following their third straight victory, began a stretch of four consecutive games against teams with losing records (Washington, Brooklyn and Detroit).
Greivis Vasquez led Sacramento with 20 points and DeMarcus Cousins added 17 points, eight rebounds and seven assists.
PISTONS 109, NETS 97
NEW YORK • Reserve Rodney Stuckey scored a season-high 27 points and Detroit sent Brooklyn to a fifth straight loss and sole possession of last place in the Atlantic Division.
The Nets, with their enormous payroll and enormous expectations, fell to 3-10, a half-game behind the New York Knicks, and were hearing boos at Barclays Center in the second half.
Greg Monroe had 18 points and 11 rebounds for the Pistons, who bounced back from consecutive losses to Atlanta. Brandon Jennings added 14 points and 10 assists, making all 10 free throws to make up for a 2-for-10 shooting performance.
Joe Johnson made eight 3-pointers and scored a season-high 34 points, but the short-handed Nets couldn't overcome another cold night from Paul Pierce and Kevin Garnett, who were a combined 7 for 22.
SUNS 104, MAGIC 96
ORLANDO, Fla. • Goran Dragic scored 23 points and Gerald Green added 20 to lead Phoenix over Orlando.
Two days after stopping a four-game losing streak at Charlotte, the Suns took the lead early in the first quarter and never relinquished it.
After Orlando trimmed what had been a 14-point deficit to three late in the fourth quarter, Channing Frye made a difficult jumper and Dragic scored the game 's next seven points to put it away.
Dragic made 10 of 17 shots and also had 13 assists. Frye finished with 14 points and seven rebounds.
Nikola Vucevic led Orlando with 20 points. Andrew Nicholson had 19 off the bench and Aaron Afflalo added 12 for the Magic, who have lost four straight games and seven of eight overall.