Looking past the Gators, several interesting round-of-32 matchups could await in this region, including New Mexico-Kansas. The Lobos, who expected to be a high seed, could make a deep run into the tournament as a No. 7 seed, though getting past the Jayhawks would be no easy task. The Jayhawks boast one of the most talented rosters in college basketball, with freshman stars Andrew Wiggins and Joel Embiid who both appear to be surefire NBA Draft lottery picks leading the way.
Another intriguing team in the South is Syracuse. The Orange climbed to No. 1 in the country and were undefeated late into the season, but enter the tournament reeling after losing five of their last seven games.
It's almost impossible to predict a No. 14 over a No. 3 upset, but the Orange will have to prove they can avoid a total collapse one which would be complete if Western Michigan can pull off the stunner.
Whatever happens, one thing is certain: Whoever emerges from the South will have earned its trip to the Final Four after navigating a difficult region.
No. 1 Florida (32-2) vs. No. 16 Albany (17-14)/ Mount St. Mary's (16-16)
At Orlando, Fla. | Thursday, 2:10 p.m., TBS
Outlook • The top-ranked Gators should have no problem against the winner of the No. 16-seed play-in game. Both Albany and Mount St. Mary's upset favored teams in their respective conference tournament finals.
No. 2 Kansas (24-9) vs. No. 15 Eastern Kentucky (24-9)
At St. Louis | Friday, 2:10 p.m., TBS
Outlook • Led by freshman star Andrew Wiggins, one of the best players in the country, Kansas should have little trouble dispatching the Colonels, though the Jayhawks lost three of their last five games. For those keeping score, this is the Jayhawks' 25th consecutive NCAA appearance.
No. 3 Syracuse (27-5) vs. No. 14 Western Michigan (23-9)
At Buffalo, N.Y. | Thursday, 12:45 p.m., Ch. 2
Outlook • Syracuse looked like a No. 1 seed halfway through the season, then went into a nosedive that proved costly. Still, the Orange are playing close to home and the Mid-America Conference Broncos don't pose much of a threat. Can Syracuse get past Saturday? Stady tuned.
No. 4 UCLA (26-8) vs. No. 13 Tulsa (21-12)
At San Diego | Friday, 7:57 p.m., truTV
Outlook • Fresh off of its Pac-12 tournament title win over Arizona, UCLA is looking to continue its hot run. The Bruins are loaded with talent, but first-year Bruins coach Steve Alford will be scrutinized after past postseason failures. And Tulsa also is on a roll, winning its last 11 games.
No. 5 Virginia Commonwealth (26-8) vs. No. 12 Stephen F. Austin (31-2)
At San Diego | Friday, 5:27 p.m., truTV
Outlook • VCU has been a darling of recent NCAA Tournaments, but the Rams who fell in the A-10 championship game to St. Joseph's will have to dodge a potential early upset from a more than capable opponent in the Lumberjacks.
No. 6 Ohio State (25-9) vs. No. 11 Dayton (23-10)
At Buffalo, N.Y. | Thursday, 10:15 a.m., Ch. 2
Outlook • Dayton entered Selection Sunday firmly on the bubble and many thought the Flyers would be in a play-in game in their hometown while No. 24 Ohio State got bounced in the Big Ten semifinals. This marks the first time in five years the Buckeyes are lower than a No. 5 seed.
No. 7 New Mexico (27-6) vs. No. 10 Stanford (21-12)
At St. Louis | Friday, 11:40 a.m., TBS
Outlook • Fresh off its Mountain West championship game win over San Diego State, New Mexico seems under-seeded here. Translation: the solid-but-unspectacular Cardinal will have their hands full. If the Lobos are battle-tested, they don't have a great NCAA Tournament history.
No. 8 Colorado (23-11) vs. No. 9 Pittsburgh (25-9)
At Orlando, Fla. | Thursday, 11:40 a.m., TBS
Outlook • This matchup appears even and could go down to the wire. The Buffaloes finished fourth in the Pac-12, but will be without their best player, Spencer Dinwiddie, while the Panthers were fifth in their first season in the ACC.
Andrew Wiggins, Kansas. The most highly touted freshman coming into this season, Wiggins did not disappoint. There were some speed bumps, but he lived up to the hype.
Florida. The Gators are the No. 1 team in the country and cruised through the SEC, topped with Sunday's win over Kentucky in the conference title game. Their path to the Sweet 16 is not without potholes talented UCLA could be waiting for them. But a Final 4 trip is likely.
New Mexico. The Lobos capped a marvelous season with a victory over San Diego State in the Mountain West title game. As a No. 7, they are underseeded, making them a tempting pick to get to the round of 32 and perhaps beyond. Kansas, take note.
Best player you don't know
Glenn Kosey, Eastern Kentucky. Kosey established himself as one of the better guards in the country, averaging 18.8 points a game to lead the Colonels to the tournament.